Yusei is a new and main character in this series. He is considered a rare duelist riding [Red D-Wheel]. Yusei is familiar with machine and computer, so he assembles D-Wheel by himself. His personality is very different from Judai in GX series but similar to Mutou Yugi. He looks cool and smart with hot heart especially in a duel and always thinks about his friends. After fighting Jack Atlas, [Dragon's Birthmark] appears on his arm and makes him become a [Signer ~ シグナー].

The story mainly focuses on Yusei. As people live in gorgeous Neo Domino City, he lives with his scums in the old Satellite plant. Yusei assembles his D-Wheel from any material he can get from this junk place. This is the source of his deck's concept of Junk (ie. Junk Warrior). Yusei plans to have a decisive battle with Jack because Jack stole his D-Wheel and ace card.