Mito Uzumaki (うずまきミト, Uzumaki Mito) was a kunoichi who originated from Uzushiogakure's Uzumaki clan and later married into Konohagakure's Senju clan. She was also the first jinchūriki of Kurama the Nine-Tailed Demon Fox.
Manga Debut: Chapter #500
Anime Debut: Naruto Shippuuden Episode #247
(source: Narutopedia)