Ratchet was the Autobot medic, and therefore he seldom was ever seen in battle. He usually spent time at the Autobot base with Wheeljack creating and repairing other Autobots. The two of them were credited for creating the Dinobots in an attempt to bolster their ranks versus the Decepticons.

Ratchet was eventually killed in The Transformers: The Movie in an attack by the Decepticons on an Autobot shuttle. The Decepticons penetrated the hull of the shuttle that he, Ironhide, Prowl, and Brawn were flying in. Ironhide and Ratchet attacked the invaders together after Prowl and Brawn's death. The two suffered the same amount of fire from the Decepticons but due to Ironhide's strong armor he survived the first strike ultimately dying in the end, Ratchet on the other hand was killed easily.

Following the movie, the Autobot First Aid became the Autobot's chief medic.